Enterprise Evidence Report · NR-REPORT-V2.0

United States
Neuroscience Intelligence

United States neuroscience evidence report: current clinical, research, institution and source-linked intelligence.

Evidence rank #1 of 50 · Data maturity A · Research score 66.2 · Data confidence 100.0 / 100 · Snapshot 2026-10-12 03:36 UTC.

⚗
2,513Curated trials
↗
498Recruiting trials
▦
5,818Publications
⌂
1,972Institutions

Executive interpretation

United States ranks #1 in the current NeuroRisk evidence-ranked market layer. This ranking summarizes indexed clinical, publication and institution evidence; it is not a probability of commercial success and not an investment recommendation.

Methodology status

Methodology NR-REPORT-V2.0. No synthetic ML confidence is presented as scientific probability. Counts and source links below are tied to the generation snapshot.

Methodology →

Leading sponsors

Massachusetts General Hospital7016 recruiting
University of California, Los Angeles408 recruiting
Stanford University3613 recruiting
Pfizer342 recruiting
Yale University318 recruiting
University of Michigan319 recruiting
Duke University305 recruiting
Eli Lilly and Company305 recruiting
Johns Hopkins University297 recruiting
National Institute of Neurological Disorders and Stroke (NINDS)282 recruiting

Disease activity

Alzheimers337trials
Parkinsons301trials
Autism275trials
Epilepsy227trials
Depression215trials
Adhd196trials
Other Neurology88trials
Stroke76trials
Pain Neuropathy74trials
Other Psychiatry65trials

Research institutions

Boise State UniversityOpenAlexlinked institution
Southern States UniversityOpenAlexlinked institution
Banner HealthOpenAlexlinked institution
Pacific Northwest Research StationOpenAlexlinked institution
Agricultural Research ServiceOpenAlexlinked institution
Brown FoundationOpenAlexlinked institution
Spaulding Rehabilitation HospitalOpenAlexlinked institution
Fielding Graduate UniversityOpenAlexlinked institution

Clinical evidence trail

NCT07837973Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight LossRECRUITING
NCT07824206Lumateperone Added to Antidepressant Therapy in Adults With Major Depressive Disorder Experiencing Emotional BluntingNOT_YET_RECRUITING
NCT07812987Rapid Entrainment and Signal-guided Neuromodulation for Behavioral HealthACTIVE_NOT_RECRUITING
NCT07805382Dynamic Relationships Between Estrogen Fluctuations, Sleep, and Psychiatric Complexity Among Adolescent Females With ADHDNOT_YET_RECRUITING
NCT07804615A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic TherapyRECRUITING
NCT07798297Transitional Intervention for Hyperacusis in AutismRECRUITING
NCT07793097Can Mindfulness and Virtual Reality Reduce Stress in Young Adults With Type 1 Diabetes?NOT_YET_RECRUITING
NCT07793045Binaural Beats Stimulation for Adults With Attention-Deficit/Hyperactivity DisorderRECRUITING
NCT07779785VICA: A Virtual Care Assistant for Dementia CaregiversNOT_YET_RECRUITING
NCT07770152Semaglutide in Youth With Autism Spectrum DisorderNOT_YET_RECRUITING
NCT07759154A Study to Test the Effects of Centanafadine in Adults With Attention-deficit/Hyperactivity Disorder and Emotional DysregulationRECRUITING
NCT07758270Brain Imaging and Immune Changes During Remibrutinib Treatment in Multiple Sclerosis.RECRUITING

Research evidence trail

PUBMEDComparative Screening of Alzheimer's Disease, Lewy Body Dementia, and Frontotemporal Dementia Using miRNA and Machine Learning.2027-01-01
PUBMEDSystematic Dissection of Key Driver Perturbation Signatures in Single Cells via ECCITE-seq.2027-01-01
PUBMEDA Standardized Protocol for Generating iPSC-Derived Human Microglia for Functional Genomic Assays.2027-01-01
PUBMEDSilent signals: Autism, disability, and heat vulnerability in a warming world.2026-12-31
PUBMEDDevelopment of a novel analysis method for evaluating PTSD-like behavior in mice based on DSM-V criteria.2026-12-31
PUBMEDGut Proteobacteria glycine metabolism regulates neuroplasticity, motivation, and reinstatement of cocaine self-administration in mice.2026-12-31
PUBMEDDynamic flexibility of the murine gut microbiota during morphine disturbance enables escape from the stable dysbiosis that is associated with addiction-like behavior.2026-12-31
PUBMEDEffects of transcutaneous cervical vagus nerve stimulation on autonomic function in posttraumatic stress disorder and opioid use disorder.2026-12-31
PUBMEDNutritional regulation of gut-brain immune crosstalk across the lifespan.2026-12-31
PUBMEDEpidemiology of bipolar disorder with concomitant pregnancy-induced hypertension and associated pharmacotherapies in the United States, Canada and Saudi Arabia over a five-year period (2019-2023).2026-12-31
PUBMEDThe evolution of character education in medicine.2026-12-31
PUBMEDUtility of the brief Patient Health Questionnaire-2 and Generalized Anxiety Disorder-2 screeners for depression and generalized anxiety symptom identification in people with human immunodeficiency virus.2026-12-31

World Bank context

IT.NET.USER.ZSinternet_users_pct94.7% · 2024
NY.GDP.MKTP.CDgdp_current_usd$28,751.0B · 2024
NY.GDP.PCAP.CDgdp_per_capita_usd$84,534 · 2024
SE.PRM.ENRRschool_enrollment_primary_pct96.97 · 2022
SE.SEC.ENRRschool_enrollment_secondary_pct97.47 · 2022
SH.XPD.CHEX.GD.ZScurrent_health_expenditure_pct_gdp16.7% · 2023
SH.XPD.CHEX.PC.CDcurrent_health_expenditure_per_capita_usd$13,473 · 2023
SH.XPD.GHED.GD.ZSgovernment_health_expenditure_pct_gdp9.0% · 2023
SP.DYN.CBRT.INbirth_rate_crude10.60 · 2024
SP.POP.TOTLpopulation_total340,110,988 · 2024
SP.URB.TOTL.IN.ZSurban_population_pct80.1% · 2024

Macro indicators are shown only where a timestamped World Bank source row exists. They are context, not NeuroRisk predictions.

Sources and provenance

ClinicalTrials.gov provides NCT evidence. PubMed/NCBI and OpenAlex provide research metadata. OpenAlex links institutions. World Bank indicators are included only when an explicit source row and year exist. NeuroRisk transformations add normalization, ranking and graph connections.

Limitations

Indexed corpus counts are not guaranteed exhaustive global totals. Scores are comparative decision-support signals. This report is not medical advice, regulatory advice, patent clearance, an investment recommendation or a guarantee of outcome.